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High Quality Content by WIKIPEDIA articles! An analgesic (also known as a painkiller) is any member of the group of drugs used to relieve pain (achieve analgesia). The word analgesic derives from Greek an- (“without”) and algos (“pain”). Analgesic drugs act in various ways on the peripheral and central nervous systems; they include paracetamol (para-acetylaminophenol, also known in the US as acetaminophen), the non-steroidal anti-inflammatory drugs (NSAIDs) such as the salicylates, narcotic drugs such as morphine, synthetic drugs with narcotic properties such as tramadol.. In choosing analgesics, the severity and response to other medication determines the choice of agent; the WHO pain ladder, originally devel… More >> Painkiller: Pharmaceutical Drug, Pain, Peripheral Nervous System, Non-Steroidal Anti-Inflammatory Drug, Central Nervous System, Narcotic, Morphine, Pain Ladder, Tramadol